We use experimental and computational approaches to study how RNA processing controls gene expression

We have open positions for graduate students, postdocs, research technicians, and undergraduate students
please inquire at didoming@email.unc.edu
(prospective postdocs should include a brief statement of research interests and CV)

Experimental

We use a variety of experimental techniques including:

  • High-throughput biochemical techniques to understand how proteins bind RNA. see

  • In vivo and in vitro approaches to determine how short sequence elements control RNA processing. 

  • Cell based-approaches to study how processing factors modulate cell signaling and drug response. see

Computational

We use a variety of computational approaches to explore:

  • Aberrant RNA processing (e.g. splicing) in human cancers.

  • RNA binding protein specificities and binding kinetics.

  • Relationships between gene regulatory programs and drug response.